Circadian clocks play a key role in fat cell growth

Journal References: Stefan Tholen, Roma Patel, Agnieszka Agas, Kyle M. Kovary, Atefeh Rabiee, Hayley T. Nicholls, Ewa Bielczyk-Maczyńska, Wenting Yang, Fredric B. Kraemer, Mary N. Teruel. Flattening of circadian glucocorticoid oscillations drives acute hyperinsulinemia and adipocyte hypertrophy. Cell Reports, 2022; 39 (13): 111018 DOI: 10.1016/j.celrep.2022.111018 Zhi-Bo Zhang, Joydeb Sinha, Zahra Bahrami-Nejad, Mary N. Teruel. The … Read more

A role for cell ‘antennae’ in managing dopamine signals in the brain

Journal Reference: Toneisha Stubbs, Andrew Koemeter-Cox, James I. Bingman, Fangli Zhao, Anuradha Kalyanasundaram, Leslie A. Rowland, Muthu Periasamy, Calvin S. Carter, Val C. Sheffield, Candice C. Askwith, Kirk Mykytyn. Disruption of dopamine receptor 1 localization to primary cilia impairs signaling in striatal neurons. The Journal of Neuroscience, 2022; JN-RM-0497-22 DOI: 10.1523/JNEUROSCI.0497-22.2022 The research was conducted … Read more

‘Easy yet highly effective’: Seeing cell secretion like never before

Journal Reference: Anushree Seth, Ekansh Mittal, Jingyi Luan, Samhitha Kolla, Monty B. Mazer, Hemant Joshi, Rohit Gupta, Priya Rathi, Zheyu Wang, Jeremiah J. Morrissey, Joel D. Ernst, Cynthia Portal-Celhay, Sharon Celeste Morley, Jennifer A. Philips, Srikanth Singamaneni. High-resolution imaging of protein secretion at the single-cell level using plasmon-enhanced FluoroDOT assay. Cell Reports Methods, 2022; 100267 … Read more

Vitamin K prevents cell loss of life: New function for a long-known molecule

Journal Reference: Eikan Mishima, Junya Ito, Zijun Wu, Toshitaka Nakamura, Adam Wahida, Sebastian Doll, Wulf Tonnus, Palina Nepachalovich, Elke Eggenhofer, Maceler Aldrovandi, Bernhard Henkelmann, Ken-ichi Yamada, Jonas Wanninger, Omkar Zilka, Emiko Sato, Regina Feederle, Daniela Hass, Adriano Maida, André Santos Dias Mourão, Andreas Linkermann, Edward K. Geissler, Kiyotaka Nakagawa, Takaaki Abe, Maria Fedorova, Bettina Proneth, … Read more

A ‘nano-robot’ built entirely from DNA to explore cell processes

Journal Reference: A. Mills, N. Aissaoui, D. Maurel, J. Elezgaray, F. Morvan, J. J. Vasseur, E. Margeat, R. B. Quast, J. Lai Kee-Him, N. Saint, C. Benistant, A. Nord, F. Pedaci, G. Bellot. A modular spring-loaded actuator for mechanical activation of membrane proteins. Nature Communications, 2022; 13 (1) DOI: 10.1038/s41467-022-30745-2 Our cells are subject to … Read more

New solution for stem cell manufacturing

Journal Reference: Lin Ding, Sajad Razavi Bazaz, Mahsa Asadniaye Fardjahromi, Flyn McKinnirey, Brian Saputro, Balarka Banerjee, Graham Vesey, Majid Ebrahimi Warkiani. A modular 3D printed microfluidic system: a potential solution for continuous cell harvesting in large-scale bioprocessing. Bioresources and Bioprocessing, 2022; 9 (1) DOI: 10.1186/s40643-022-00550-2 Stem cells offer great promise in the treatment of many … Read more

Cheaper hydrogen fuel cell could mean better green energy options

Journal Reference: Mehmood, A., Gong, M., Jaouen, F. et al. High loading of single atomic iron sites in Fe–NC oxygen reduction catalysts for proton exchange membrane fuel cells. Nat Catal, 2022 DOI: 10.1038/s41929-022-00772-9 Hydrogen fuel cells convert hydrogen to electricity with water vapour as the only by-product, making them an attractive green alternative for portable … Read more

High performance microscopy for non-invasive conjunctival goblet cell examination

Journal Reference: Jungbin Lee, Seonghan Kim, Jeongho Kim, Byeong Jae Son, Chang Ho Yoon, Hong Kyun Kim, Ki Hean Kim. Moxifloxacin-Based Extended Depth-of-Field Fluorescence Microscopy for Real-Time Conjunctival Goblet Cell Examination. IEEE Transactions on Medical Imaging, 2022; 1 DOI: 10.1109/TMI.2022.3151944 A POSTECH research team led by Professor Ki Hean Kim and Ph.D. candidates Jungbin Lee … Read more

Study shows easy, computationally-light model can simulate complex brain cell responses

Journal Reference: Yota Tsukamoto, Honami Tsushima, Tohru Ikeguchi. Non-periodic responses of the Izhikevich neuron model to periodic inputs. Nonlinear Theory and Its Applications, IEICE, 2022; 13 (2): 367 DOI: 10.1587/nolta.13.367 Learning how neurons respond to different signals can further the understanding of cognition and development and improve the management of disorders of the brain. But … Read more

A key brain region for substance use disorders now has a searchable atlas of distinct cell populations

Journal Reference: Robert A. Phillips, Jennifer J. Tuscher, Samantha L. Black, Emma Andraka, N. Dalton Fitzgerald, Lara Ianov, Jeremy J. Day. An atlas of transcriptionally defined cell populations in the rat ventral tegmental area. Cell Reports, 2022; 39 (1): 110616 DOI: 10.1016/j.celrep.2022.110616 The VTA is important for its role in the dopamine neurotransmission involved in … Read more

Cool N Spicy