HIV speeds up body’s aging processes soon after an infection, study shows

Journal Reference: Elizabeth Crabb Breen, Mary E. Sehl, Roger Shih, Peter Langfelder, Ruibin Wang, Steve Horvath, Jay H. Bream, Priya Duggal, Jeremy Martinson, Steven M. Wolinsky, Otoniel Martínez-Maza, Christina M. Ramirez, Beth D. Jamieson. Accelerated aging with HIV begins at the time of initial HIV infection. iScience, 2022; 104488 DOI: 10.1016/j.isci.2022.104488 The findings suggest that … Read more

Helping prevent transmission of HIV from mother to child during breastfeeding

Journal Reference: Allison S. Thomas, Carolyn Coote, Yvetane Moreau, John E. Isaac, Alexander C. Ewing, Athena P. Kourtis, Manish Sagar. Antibody-dependent cellular cytotoxicity (ADCC) responses along with ADCC susceptibility influence HIV-1 mother to child transmission. JCI Insight, 2022; DOI: 10.1172/jci.insight.159435 Researchers evaluated ADCC and neutralizing antibody (nAb) properties in pre-transmission plasma from HIV-1 exposed infants … Read more

HIV: The antibodies of ‘post-treatment controllers’

Journal Reference: Luis M. Molinos-Albert, Valérie Lorin, Valérie Monceaux, Sylvie Orr, Asma Essat, Jérémy Dufloo, Olivier Schwartz, Christine Rouzioux, Laurence Meyer, Laurent Hocqueloux, Asier Sáez-Cirión, Hugo Mouquet, Thierry Prazuck, Barbara De Dieuleveult, Firouzé Bani-Sadr, Maxime Hentzien, Jean-Luc Berger, Isabelle Kmiec, Gilles Pichancourt, Safa Nasri, Gilles Hittinger, Véronique Lambry, Anne-Cécile Beauey, Gilles Pialoux, Christia Palacios, Martin … Read more

Antibiotic and antiretroviral drug effects on breast milk are explored for mothers living with HIV

Journal Reference: Rabia Maqsood, Peter T. Skidmore, LaRinda A. Holland, Joshua L. Au, Adam K. Khan, Lily I. Wu, Ningxin Ma, Emily R. Begnel, Bhavna H. Chohan, Judith Adhiambo, Grace John-Stewart, James Kiarie, John Kinuthia, Michael H. Chung, Barbra A. Richardson, Jennifer Slyker, Dara A. Lehman, Efrem S. Lim. Dynamic Changes in Breast Milk Microbiome … Read more

HIV drug stabilizes disease progression in metastatic colorectal cancer

Journal Reference: Mihir Rajurkar, Aparna R. Parikh, Alexander Solovyov, Eunae You, Anupriya S. Kulkarni, Chong Chu, Katherine H. Xu, Christopher Jaicks, Martin S. Taylor, Connie Wu, Katherine A. Alexander, Charly R. Good, Annamaria Szabolcs, Stefanie Gerstberger, Antuan V. Tran, Nova Xu, Richard Y. Ebright, Emily E. Van Seventer, Kevin D. Vo, Eric C. Tai, Chenyue … Read more

‘An underutilized software:’ UV-LED lights can kill coronaviruses and HIV with the flip of a change, study finds

‘An underutilized software:’ UV-LED lights can kill coronaviruses and HIV with the flip of a change, study finds – NovLink Home Mash C ‘An underutilized software:’ UV-LED lights can kill coronaviruses and HIV with the flip of a change, study finds We would love to give thanks to the author of this post for this … Read more

CRISPR and HIV: New technique in human blood unveils potential paths toward cure

Journal Reference: Joseph Hiatt, Judd F. Hultquist, Michael J. McGregor, Mehdi Bouhaddou, Ryan T. Leenay, Lacy M. Simons, Janet M. Young, Paige Haas, Theodore L. Roth, Victoria Tobin, Jason A. Wojcechowskyj, Jonathan M. Woo, Ujjwal Rathore, Devin A. Cavero, Eric Shifrut, Thong T. Nguyen, Kelsey M. Haas, Harmit S. Malik, Jennifer A. Doudna, Andrew P. … Read more

New study reveals why HIV remains in human tissue even after antiretroviral therapy

Journal Reference: Shima Shahbaz, Isobel Okoye, Gregg Blevins, Shokrollah Elahi. Elevated ATP via enhanced miRNA-30b, 30c, and 30e downregulates the expression of CD73 in CD8 T cells of HIV-infected individuals. PLOS Pathogens, 2022; 18 (3): e1010378 DOI: 10.1371/journal.ppat.1010378 Now, new research by University of Alberta immunologist Shokrollah Elahi reveals a possible answer to the mystery … Read more

High prevalence of cancer among men living with HIV, study shows

Journal References: Siran M. Koroukian, Guangjin Zhou, Suparna M. Navale, Nicholas K. Schiltz, Uriel Kim, Johnie Rose, Gregory S. Cooper, Scott Emory Moore, Laura J. Mintz, Ann K. Avery, Sudipto Mukherjee, Sarah C. Markt. Excess cancer prevalence in men with HIV: A nationwide analysis of Medicaid data. Cancer, 2022; DOI: 10.1002/cncr.34166 Cathy J. Bradley, Lindsay … Read more

Intermingling between populations may contribute to HIV spread

Journal Reference: Lerato E Magosi, Yinfeng Zhang, Tanya Golubchik, Victor DeGruttola, Eric Tchetgen Tchetgen, Vladimir Novitsky, Janet Moore, Pam Bachanas, Tebogo Segolodi, Refeletswe Lebelonyane, Molly Pretorius Holme, Sikhulile Moyo, Joseph Makhema, Shahin Lockman, Christophe Fraser, Myron Max Essex, Marc Lipsitch. Deep-sequence phylogenetics to quantify patterns of HIV transmission in the context of a universal testing … Read more

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